Knock out Mastitis
This is a restricted veterinary medicine. This product is available only under veterinary authorisation. Managing immune function, restoring energy balance and providing effective therapy for periparturient diseases during The Vital 90 Days™ – i.e. the critical period from two months before calving to one month after calving – helps to protect the cow’s lactation potential by minimising transition disorders and maximising productivity.
Tylan™ 200 Injection is the first choice for the parenteral therapy of periparturient diseases. It contains 200 mg/mL of the active ingredient, tylosin, which has extremely low Minimum Inhibitory Concentrations (MIC) against most pathogens associated with mastitis, metritis, pneumonia and foot rot.1 Tylosin has an antibacterial spectrum that is essentially gram-positive. It is also active against certain gram-negative organisms and mycoplasma species.
Early detection and treatment with an effective antibiotic during the early stages of infection will minimise long-term tissue damage, allowing the quarter to return to normal milk production in subsequent lactations. Tylan™ 200 Injection is highly effective against the key pathogens associated with mastitis, including Staphylococcus aureus and Streptococcus uberis1, making it an excellent choice for those situations when there is a mixed pathogen spectrum or the causative agent is unknown.
Tylan™ 200 Injection is ideal for use in those cases where cows do not respond to IMM therapy or where it may be compromised by swelling of the mammary gland. Alternatively, Tylan™ 200 Injection can provide augmented treatment in combination with IMM therapies, particularly against mixed infections. Another found combination therapy incorporating Tylan™ 200 Injection produced a 12.9% higher treatment success rate against S. agalactiae compared to IMM penicillin.3
First choice for controlling metritis
Tylan™ 200 Injection is effective against pathogens that attack the reproductive tract and cause metritis, including Trueperella pyogenes (previously known as Actinomyces pyogenes), Staphylococcus aureus, Streptococcus spp, Fusobacterium necrophorum and Clostridium spp.1,2 One study showed Tylan™ 200 Injection is still fighting bacteria at the site of infection while being virtually undetectable in the blood, even 30 hours after injection.4
First choice for controlling respiratory disease
Tylan™ 200 Injection moves rapidly to the lungs, where it begins to accumulate within 30 minutes of injection. It controls a range of pathogens associated with respiratory disease, including Acholeplasma laidlawii, Clostridium perfringens, Fusobacterium necrophorum, Haemophilus somnus, Mycoplasma bovirhinus, Mycoplasma bovis, Mycoplasma dispar, Pasteurella haemolytica and Pasteurella multocida.1,2
First choice for controlling footrot
Tylan™ 200 Injection is effective against a variety of bacteria, including Trueperella pyogenes (previously known as Actinomyces pyogenes) and Fusobacterium necrophorum, associated with foot rot.1,2