Hemicell™ Liquid Supreme (β-Mannanase)

The energy sparing enzyme

β-Mannans (beta-galactomannans) are antinutritive fibres found in common feed ingredients, including soybean meal and other leguminous feeds.¹ β-Mannans have a molecular pattern similar to some pathogens, which triggers a Feed-Induced Immune Response (FIIR) in pigs. This unnecessary innate immune system stimulation consumes energy and other valuable nutrients.^2,3

Hemicell™ breaks down β-mannans to spare energy for performance. Whilst most enzyme products are energy-releasing enzymes – they “open up” feed components the animal is unable to access on its own – Hemicell™ is an energy-sparing enzyme. By breaking down β-mannans in feed, Hemicell™ minimises the metabolisable energy (ME) loss caused by the FIIR from β-mannans, allowing more energy to be available for growth and performance.^3,4

Important Safety Information

Always read and follow the label directions.

Hemicell™ is considered a ‘Generally Recognised As Safe’ (GRAS) product and has no withholding period or restrictions when used in combination with other feed ingredients.

Directions For Use

• Dilute 0.14 kg of Hemicell-L to one (1) kg using potable water and an in-line dilution system, and immediately spray apply the diluted Hemicell-L to a metric ton of mash or pelleted feed. Hemicell-L is intended to be used on mash feed or post-pelleting as it is not stable to commercial pelleting conditions.

References

¹ Hsiao, H., Anderson, D. and Dale, N. 2006. "Levels of β-mannan in Soybean Meal". Poultry Sci. 85: 1430-1432.

² Ausubel, F. 2005. "Are innate immune signaling pathways in plants and animals conserved?" Nature Immunol. 6(10): 973-979.

³ Zhang, L. and Tizard, I. (1996). “Activation of a mouse macrophage cell line by acemannan: The major carbohydrate fraction from Aloe vera gel”. Immunopharmacology. 35, 119-128.

⁴ Korver, D. 2006. "Overview of the Immune Dynamics of the Digestive System". J. Appl. Poultry Res. 15: 123-135.